ineffective erythropoiesis

New therapies to restore red cell production for patients with inherited and acquired anemias

Restoring regulation of hepcidin - the link between genetics and erythropoiesis

Congenital and acquired anemias often start with genetic alterations, but end with impaired iron mobilization and metabolism. Disc is applying new insights in hepcidin biology to restore red cell production in conditions of both iron sequestration and iron overload.

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New life in hematology

Blood transfusions have been the foundation of hematology for 50 years, and the risk/benefit of regular transfusion is not appropriate for many patients. We recognize and seek to alleviate the challenges faced by individuals with congenital anemias, myelodysplastic syndrome, myeloproliferative disorders, thalassemia, and anemia of chronic disease – both those who receive transfusions and those who don’t.

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Experienced team

Disc Medicine is led by an experienced team of scientists and industry experts, and supported by a panel of advisors with a strong track record of discovering and developing new and innovative therapies. Disc Medicine was founded by Atlas Venture and Brian MacDonald, with Novo Ventures and Access Biotechnology joining as additional investors.

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In The News

Disc Medicine to Present at the Pi…

CAMBRIDGE, Mass. (November 23, 2020) – Disc Medicine, a hematology company dedicated to the discovery and development of novel therapeutic candidates for s…

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Disc Medicine Expands Scientific A…

Tomas Ganz, MD, PhD and Elizabeta Nemeth, PhD to Join Disc Medicine Scientific Advisory Board Cambridge, Mass. – October 13, 2020 – Disc Medicine, a comp…

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Disc Medicine to Present at Citi's…

Cambridge, Mass. – September 8, 2020 – Disc Medicine, a biotechnology company dedicated to the discovery and development of novel therapeutic candidates …

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