Careers

Senior Medical Director

COMPANY OVERVIEW:

Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering, developing, and commercializing novel treatments for patients who suffer from serious hematologic diseases. We are building a portfolio of innovative, first-in-class therapeutic candidates that aim to address a wide spectrum of hematologic diseases by targeting fundamental biological pathways of red blood cell biology, specifically heme biosynthesis and iron homeostasis. Disc Medicine values collaboration, professional development, and scientific integrity and promotes an inclusive company culture that empowers and inspires.

POSITION OVERVIEW:

Disc Medicine has an exciting opportunity for an ambitious physician to be a Senior Medical Director. Reporting to the CMO, this position will support the two clinical-stage programs focused on iron metabolism. The Medical Director will work with the cross-functional program team to drive the clinical program from Phase 1 to pivotal trials across a number of indications.

RESPONSIBILITIES:

• Lead the clinical study team in the planning, execution, and analysis of clinical trials.
• Represent the clinical study team at the Program Team, Clinical Subteam and Clinical Trial Team.
• Provide medical oversight of CRO clinical trial conduct.
• Lead internal and external team members, vendors, and consultants to author, review and evaluate regulatory submissions.
• Be responsible for the clinical content of all clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CRFs, annual IND reports, CSRs, and clinical expert reports.
• Be responsible for the clinical content of all clinical and regulatory documents, including protocols, INDs, CTAs, investigator brochures, CRFs, annual IND reports, CSRs, and clinical expert reports.
• Participate in Investigator meeting planning and execution and/or on-site initiation meetings.
• Organize and present at relevant clinical advisory boards, DMC and medical/scientific meetings.
• Support business development processes by providing medical expertise for in- or out-licensing, partnering and acquisition activities.
• Develop and maintain relationships and serve as the main medical liaison with key opinion leaders and principal investigators.
• Collaborate closely with the internal research team to integrate translational research into development and clinical strategies.
• Maintain awareness of internal and external developments (scientific, clinical, competitive, and regulatory) that could impact the development plan, including attendance at major scientific conferences, participation in competitive intelligence activities, and periodic literature review.
• Critically evaluate available information about diseases of interest to the therapeutic area and the competitive landscape and synthesize information succinctly to support dissemination and incorporation into clinical development programs, asset plans and therapeutic area strategy
• Travel, as needed, nationally and internationally.

REQUIREMENTS:

• MD with research experience or MD/PhD; fellowship training in hematology, oncology, nephrology, gastroenterology, cardiology preferred.
• Extensive experience in translational or clinical research related to drug development is required: biotech/ pharma experience preferred.
• Experience with developing clinical regulatory strategy and authoring regulatory submissions.
• Strong academic record with high quality peer-reviewed publications that demonstrate critical thinking ability.
• Strong clinical development process understanding, including knowledge of the multidisciplinary functions involved.
• Track record of effective cross-collaboration within an organization, among teams, and external groups/organizations.
• Ability to proactively integrate multiple perspectives into the clinical development process for best end-results.
• A willingness to take on new responsibilities, possess a strong attention to detail with a commitment to thoroughness.
• Ability to write cogently and think strategically.
• Ability to identify and build relationships with thought leaders and leading clinical centers.
• Expertise in data analysis and presentation.
• Knowledge in the principles of clinical research methodology, statistics, data analysis and interpretation
• Ability to communicate with internal and external stakeholders orally clearly and effectively and in writing.
• Experience in interacting with varying levels of internal/external management, academicians, clinicians, and scientists.

Disc Medicine is an equal opportunity employer committed to providing all qualified candidates and employees equal opportunities. We offer comprehensive benefits and competitive compensation packages. The Company headquarters are in Watertown, MA, and we provide a flexible work environment.

Disc Medicine actively recruits individuals with an entrepreneurial spirit and a drive for excellence. Interested candidates should submit a cover letter and resume to our Human Resources Department at careers@discmedicine.com and include the title of the position you are applying for in the subject line.

Please note that agency phone calls or submissions will not be accepted.